Search results for "Apolipoprotein C2"
showing 3 items of 3 documents
Variations of lipid and apolipoprotein content in lipoproteins during fasting in European sea bass (Dicentrarchus labrax L.)
1997
Lipoproteins are involved in transport of exogenous and endogenous lipids. For this reason, the lipoprotein pattern undergoes drastic variation during fasting. In D. labrax, observed variations concern, the relative content of the five lipoproteins and their composition, both in lipid and apolipoprotein content. These data indicate the presence of a cascade mechanism of maturation involving very-low-density lipoprotein, (VLDL), low-density lipoprotein (LDL)-1 and LDL-2. In addition, a metabolic correlation involves VLDL and high-density lipoprotein (HDL). VLDL are functionally comparable with mammalian chylomicrons; in fact, they disappear rapidly after feeding from the chromatographic patt…
Liver is not the unique site of synthesis of beta 2-glycoprotein I (apolipoprotein H): evidence for an intestinal localization.
1997
Apolipoprotein H is a protein of about 50 kilodaltons, structurally related to the regulators of the complement activation family. Its physiological function is poorly understood but it has been implicated in lipid metabolism and coagulative pathways. The major site of synthesis is thought to be the liver. Several reports indicate that apolipoprotein H is the antigen of the antiphospholipid antibodies and also behaves as an acute-phase reactant. Moreover, 40% of plasma apolipoprotein H is associated with very low-density lipoprotein, high-density lipoprotein, and postprandial chylomicrons. In this study we investigated other sites of synthesis by reverse transcription/polymerase chain react…
Effect of rat plasma high density lipoprotein with or without apolipoprotein E on the cholesterol uptake and on the induction of the corticosteroid b…
1991
Abstract High density lipoprotein (HDL) has been shown to induce the cellular accumulation of cholesterol esters and the biosynthesis of 21-hydroxysteroids (corticosteroids) newborn rat adrenocortical cells cultivated in serum-free medium. In order to identify the component(s) of HDL responsible for these effects, we investigated the ability of rat HDL subfractions and HDL with or without apolipoprotein E to deliver cholesterol to cells and to stimulate the steroid biosynthetic pathways in adrenal cultured cells. The total cholesterol uptake from HDL 2 was greater than that observed with HDL rich in apolipoprotein E (HDL 1 and HDL c ). Furthermore, the increase of the ratio between 21-hydro…